Comments on: Conflicts of Interest http://cstpr.colorado.edu/prometheus/?p=3456 Wed, 29 Jul 2009 22:36:51 -0600 http://wordpress.org/?v=2.9.1 hourly 1 By: Ferdinand Engelbeen http://cstpr.colorado.edu/prometheus/?p=3456&cpage=1#comment-1009 Ferdinand Engelbeen Sun, 24 Apr 2005 12:42:51 +0000 http://sciencepolicy.colorado.edu/prometheusreborn/?p=3456#comment-1009 About conflicts of interest and results of investigations, I was confronted with something similar as for the BPA case. That happened when phthalates were linked to childhood asthma. While there was a large overlap between amount of phthalates in dust measured in houses of patients and non-patients, the main conclusion was an increased risk of asthma at higher phthalate levels in dust. But that is contradicted by (better controlled) laboratory animal studies at one side and epidemiological studies of workers in the phthalate/PVC industry at the other side, where occupational levels are far higher, and where asthma or (very rare) allergy cases are not increased. What the researchers failed to look at (no figures for total - inhaled - dust amount were given), is the fact that in houses with asthma patients, dust is far more controlled, including easy to clean vinyl flooring (with phthalates...), thus they probably reversed cause and effect! Main conclusion: non-industry funded studies are not necessarily more reliable than industry funded one's. Much depends on how good the individual study is set up, including all possible confounders… About conflicts of interest and results of investigations, I was confronted with something similar as for the BPA case.

That happened when phthalates were linked to childhood asthma. While there was a large overlap between amount of phthalates in dust measured in houses of patients and non-patients, the main conclusion was an increased risk of asthma at higher phthalate levels in dust. But that is contradicted by (better controlled) laboratory animal studies at one side and epidemiological studies of workers in the phthalate/PVC industry at the other side, where occupational levels are far higher, and where asthma or (very rare) allergy cases are not increased. What the researchers failed to look at (no figures for total – inhaled – dust amount were given), is the fact that in houses with asthma patients, dust is far more controlled, including easy to clean vinyl flooring (with phthalates…), thus they probably reversed cause and effect!

Main conclusion: non-industry funded studies are not necessarily more reliable than industry funded one’s. Much depends on how good the individual study is set up, including all possible confounders…

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By: Crumb Trail http://cstpr.colorado.edu/prometheus/?p=3456&cpage=1#comment-1010 Crumb Trail Fri, 15 Apr 2005 18:37:21 +0000 http://sciencepolicy.colorado.edu/prometheusreborn/?p=3456#comment-1010 <strong>Proxy Wars</strong> In Conflicts of Interest Roger Pielke illuminates the murky battle ground of science politicization. It is important to recognize that the chase of chemical risk assessment (and climate change and many others) putatively scientific debates are real pr... Proxy Wars

In Conflicts of Interest Roger Pielke illuminates the murky battle ground of science politicization. It is important to recognize that the chase of chemical risk assessment (and climate change and many others) putatively scientific debates are real pr…

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